Identification of host genes potentially implicated in the Malus pumila and ‘Candidatus Phytoplasma mali’ interactions

Two‘Candidatus Phytoplasma mali’ strains (AP and AT), were studied in experimentally infected apple trees to analyze transcriptional profiles during interaction with phytoplasmas. Three groups of sample combinations were employed: healthy - infected, symptomatic - non-symptomatic, and AP-infected - AT-infected sample. The majority of genes were differently expressed between healthy and infected samples. Changes in gene expression involved a wide spectrum of biological functions, including processes of metabolism, cell defence, photosynthesis, transport, transcription, signal transduction and protein synthesis. The possible effect of phytoplasma infection on these processes and their relationships with disease development, symptom appearance and possible plant defence system is discussed.