Coproduction of EPA and Fucoxanthin with P. tricornutum – A Promising Approach for Up- and Downstream Processing

Derwenskus, Felix; Schäfer, Benjamin; Müller, Jan; Frick, Konstantin; Gille, Andrea GND; Briviba, Karlis GND; Schmid-Staiger, Ulrike; Hirth, Thomas

Eicosapentaenoic acid (EPA) and fucoxanthin, a carotenoid, provide a broad variety of health benefits in human nutrition. In this study, an up- and downstream process for the coproduction of EPA and fucoxanthin using the diatom Phaeodactylum tricornutum in flat-panel airlift photobioreactors is proposed. The approach represents a promising alternative to conventional sources for both compounds, viz. marine fish and macroalgae. The productivity as well as the biomass-specific product content were optimized during cultivation. Subsequently, both compounds were extracted, separated and purified using pressurized liquids.

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Derwenskus, Felix / Schäfer, Benjamin / Müller, Jan / et al: Coproduction of EPA and Fucoxanthin with P. tricornutum – A Promising Approach for Up- and Downstream Processing. 2020.

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