Transcriptome analysis of the Cydia pomonella granulovirus

The Cydia pomonella Granulovirus (CpGV) is widely used for the control of codling moth (C. pomonella) many apple growing regions worldwide. In recent years development of resistance to CpGV was observed in several European countries. On the other hand, new CpGV isolates overcoming this resistance were identified and applied in orchards with resistance. To understand better the interaction between CpGV and its host and to determine the genetic factors involved in the virulence of the virus the transcriptome of the virus and the expression profile of its genome is analysed. By quantitative reverse transcription PCR (qRT-PCR) analyses, the specific time frame of the infection process in midgut and fatbody tissue shall be discovered. The aim of this project is to find new ways of virulence management by expanding the knowledge on the gene regulation of CpGV in susceptible and resistant codling moth.