Neurotropic highly pathogenic avian influenza A(H5N1) virus in red foxes, northern Germany

Baechlein, Christine; Kleinschmidt, Sven; Hartmann, Dorothee; Kammeyer, Patricia; Wöhlke, Anne; Warmann, Tobias; Herms, Louise; Kühl, Bianca; Beineke, Andreas; Wohlsein, Peter; Harder, Timm, C.; Runge, Martin

doi:10.3201/eid2912.230938

Artikel Di., 31. Okt.. 2023 CC BY 4.0

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Neurotropic highly pathogenic avian influenza A(H5N1) virus in red foxes, northern Germany

Baechlein, Christine; Kleinschmidt, Sven; Hartmann, Dorothee; Kammeyer, Patricia; Wöhlke, Anne; Warmann, Tobias; Herms, Louise; Kühl, Bianca; Beineke, Andreas; Wohlsein, Peter; Harder, Timm C.; Runge, Martin

In a 1-year survey of wild terrestrial predators in northern Germany, we found that 5 of 110 foxes were infected with contemporary avian influenza A(H5N1) viruses, forming a temporal cluster during January‒March 2023. Encephalitis and strong cerebral virus replication but only sporadic mammalian-adaptive viral polymerase basic 2 protein E627K mutations were seen.