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Long-term dietary exposure to copper in the population in Germany – Results from the BfR MEAL study

ORCID
0000-0003-2700-328X
Affiliation
German Federal Institute for Risk Assessment (BfR), Max-Dohrn-Straße 8-10, 10589, Berlin, Germany
Kolbaum, Anna Elena;
ORCID
0000-0001-5667-9524
Affiliation
German Federal Institute for Risk Assessment (BfR), Max-Dohrn-Straße 8-10, 10589, Berlin, Germany
Sarvan, Irmela;
ORCID
0000-0003-2549-8055
Affiliation
German Federal Institute for Risk Assessment (BfR), Max-Dohrn-Straße 8-10, 10589, Berlin, Germany
Bakhiya, Nadiya;
ORCID
0000-0002-0292-1482
Affiliation
German Federal Institute for Risk Assessment (BfR), Max-Dohrn-Straße 8-10, 10589, Berlin, Germany
Pieper, Robert;
ORCID
0000-0002-4405-1497
Affiliation
German Federal Institute for Risk Assessment (BfR), Max-Dohrn-Straße 8-10, 10589, Berlin, Germany
Spolders, Markus;
ORCID
0000-0002-0534-3710
Affiliation
German Federal Institute for Risk Assessment (BfR), Max-Dohrn-Straße 8-10, 10589, Berlin, Germany
Schubert, Jens;
ORCID
0000-0001-8325-250X
Affiliation
German Federal Institute for Risk Assessment (BfR), Max-Dohrn-Straße 8-10, 10589, Berlin, Germany
Jung, Christian;
ORCID
0000-0002-3959-610X
Affiliation
German Federal Institute for Risk Assessment (BfR), Max-Dohrn-Straße 8-10, 10589, Berlin, Germany
Hackethal, Christin;
ORCID
0000-0003-4346-3841
Affiliation
German Federal Institute for Risk Assessment (BfR), Max-Dohrn-Straße 8-10, 10589, Berlin, Germany
Sieke, Christian;
Affiliation
Verein Futtermitteltest (VFT, ) e.V., Haus Düsse 2, Bad Sassendorf, Germany
Grünewald, Karl-Hermann;
ORCID
0000-0003-2814-2054
Affiliation
German Federal Institute for Risk Assessment (BfR), Max-Dohrn-Straße 8-10, 10589, Berlin, Germany
Lindtner, Oliver

The German Total Diet Study (BfR MEAL Study) measured copper in 356 foods. In 105 of these foods copper was determined separately for conventionally and organically pooled samples. Mammalian liver, nuts, oilseeds, cocoa powder and chia seeds contained the highest copper levels. Organically produced foods tended to have higher levels compared to conventionally produced foods. Children's copper exposure was between 0.04 mg/kg body weight per day (mg/kg bw/day) and 0.07 mg/kg bw/day (median). High exposure (95th percentile) ranged between 0.07 mg/kg bw/day and 0.11 mg/kg bw/day. Adult's exposure ranged between 0.02 mg/kg bw/day (median) and 0.04 mg/kg bw/day (95th percentile). Grains and grain-based products were main contributors for all age groups. Copper intake was about 10% higher in a scenario where consumers select the organically produced variants. Children's median and high exposure was above the acceptable daily intake (ADI) of 0.07 mg/kg bw/day set by the European Food Safety Authority (EFSA). However, according to EFSA's evaluation this is not of concern due to higher requirement related to growth. For adults, frequent consumers of mammalian liver exceeded the ADI in median and 95th percentile. Intake of copper-containing dietary supplements may also lead to exceedance of the ADI in all age groups.

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