Carbapenem- and cefiderocol-resistant Enterobacterales in surface waters in Kumasi, Ashanti Region, Ghana: [Preprint]

Eger, Elias; Homeier-Bachmann, Timo; Adade, Eugene; Dreyer, Sylvia; Heiden, Stefan, E.; Tawiah, Patrick, Ofori; Sylverken, Augustina, Angelina; Knauf, Sascha; Schaufler, Katharina

doi:10.1101/2023.08.04.551947

Preprint Fri Aug 4 2023 CC BY-NC-ND 4.0

published

Carbapenem- and cefiderocol-resistant Enterobacterales in surface waters in Kumasi, Ashanti Region, Ghana : [Preprint]

Eger, Elias ; Homeier-Bachmann, Timo ; Adade, Eugene; Dreyer, Sylvia ; Heiden, Stefan E.; Tawiah, Patrick Ofori; Sylverken, Augustina Angelina ; Knauf, Sascha ; Schaufler, Katharina

This study investigated the presence of extended-spectrum β-lactamase-producing Enterobacterales in selected surface waters in the Ashanti Region in Ghana. Subsequent genomic analysis revealed that one-fifth of the isolates were genotypically carbapenem-resistant. Phenotypic susceptibility testing not only confirmed their carbapenem resistance, but also uncovered two cefiderocol-resistant isolates.