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Rat feeding trials: A comprehensive assessment of contaminants in both genetically modified maize and resulting pellets

Zugehörigkeit
UR 1264 MycSA, INRA, Centre INRA de Nouvelle Aquitaine - Bordeaux, 71 av Edouard Bourlaux, Villenave d'Ornon, France
Chereau, S.;
Zugehörigkeit
Laboratoire Reproduction et Développement des Plantes, Univ. Lyon, ENS de Lyon, UCB Lyon1 CNRS, INRA, Lyon, France
Rogowsky, P.;
Zugehörigkeit
Toxalim (Research Centre in Food Toxicology), Université de Toulouse, INRA, ENVT, INP, UPS, Toulouse, France
Laporte, B.;
Zugehörigkeit
UMRS1124, Toxicologie, Pharmacologie et Signalisation cellulaire, INSERM, Univ. Paris, Descartes, Paris, France
Coumoul, X.;
Zugehörigkeit
UMR1332 Biologie du Fruit et Pathologie, INRA, Univ. Bordeaux, Plateforme Métabolome Bordeaux – MetaboHUB, Centre INRA de Nouvelle Aquitaine - Bordeaux, 71 av Edouard Bourlaux, Villenave d'Ornon, France
Moing, A.;
Zugehörigkeit
Toxalim (Research Centre in Food Toxicology), Université de Toulouse, INRA, ENVT, INP, UPS, Toulouse, France
Priymenko, N.;
GND
114280789
Zugehörigkeit
Max Rubner-Institut (MRI), Federal Research Institute of Nutrition and Food
Steinberg, Pablo;
GND
1058993402
Zugehörigkeit
Julius Kühn-Institute (JKI), Institute for Biological Control, Germany
Wilhelm, Ralf;
GND
141232439
Zugehörigkeit
Julius Kühn-Institute (JKI), Institute for Biological Control, Germany
Schiemann, Joachim;
Zugehörigkeit
Toxalim (Research Centre in Food Toxicology), Université de Toulouse, INRA, ENVT, INP, UPS, Toulouse, France
Salles, B.;
Zugehörigkeit
UR 1264 MycSA, INRA, Centre INRA de Nouvelle Aquitaine - Bordeaux, 71 av Edouard Bourlaux, Villenave d'Ornon, France
Richard-Forget, F.

We analyzed a comprehensive set of contaminants in MON810 and NK603 genetically modified (GM) maize, and their non-GM counterparts, used in a rat feeding study (the GMO90 + project). Both the maize grains and the manufactured pellets were characterized. Only minor differences in contaminant levels between GM and corresponding non-GM harvests were evidenced. Fumonisin and deoxynivalenol mycotoxins were the pollutants present in the highest amounts, with concentrations that were however largely below acceptance reference values. Our data reporting slightly higher levels of fumonisin in MON810 compared to its non-GM counterpart corroborate the lower susceptibility of insect resistant Bt maize to fumonisin-producing fungi. Traces of glyphosate (0.016 mg/kg) were evidenced in grains from NK603 treated crops. Regarding the pellets, analysis of more than 650 potentially toxic substances revealed low amounts of various mycotoxins, pesticides and heavy metals. Concentrations of contaminants quantified in the pellets were however far below the maximum level of residues values set by regulatory agencies, and no substantial differences in contaminants between GM and non-GM pellets were observed. Moreover, when comparing the contamination status of grains and pellets, we demonstrate yet again that characterizing the grains is actually not sufficient to foresee the quality of the produced pellets.

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Rechteinhaber: 2018 Elsevier Ltd.

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