Deep spatial profiling of human COVID-19 brains reveals neuroinflammation with distinct microanatomical microglia-T cell interactions: [Data set]

Schwabenland, Marius; Salié, Henrike; Tanevski, Jovan; Killmer, Saskia; Lago, Marilyn, Salvat; Schlaak, Alexandra, Emilia; Mayer, Lena; Matschke, Jakob; Püschel, Klaus; Fitzek, Antonia; Ondruschka, Ben; Mei, Henrik, E.; Boettler, Tobias; Neumann-Haefelin, Christoph; Hofmann, Maike; Breithaupt, Angele; Genc, Nafiye; Stadelmann, Christine; Saez-Rodriguez, Julio; Bronsert, Peter; Knobeloch, Klaus-Peter; Blank, Thomas; Thimme, Robert; Glatzel, Markus; Prinz, Marco; Bengsch, Bertram

doi:10.5281/zenodo.5018260

Forschungsdaten Mi., 09. Juni. 2021 CC BY 4.0

Veröffentlicht

Deep spatial profiling of human COVID-19 brains reveals neuroinflammation with distinct microanatomical microglia-T cell interactions : [Data set]

Imaging mass cytometry data (txt files and folders containing single tiffs + cell masks) generated for the analysis of postmortem brains of COVID-19 patients and control groups (multiple sclerosis and patients who received ECMO therapy).

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Deep spatial profiling of human COVID-19 brains reveals neuroinflammation with distinct microanatomical microglia-T cell…

Einordnung

Erschienen in:: Zenodo
Datum der Veröffentlichung:: 09.06.2021
DOI:: 10.5281/zenodo.5018260
Sprache:: Englisch
Ressourcentyp:: Text
Verlag:: Zenodo
Schlagwörter:: SARS-CoV-2; COVID-19; encephalopathy; brain autopsy; microglia; T cells; high-dimensional 20 imaging; neuroinflammation; single-cell analysis; mass cytometry
DDC-Sachgruppe der DNB:: 570 Biowissenschaften, Biologie
Link zum Volltext:: https://zenodo.org/record/5018260#.YO6dc-gzaUk