Experimental infection of cattle with SARS-CoV-2

Ulrich, Lorenz GND; Wernike, Kerstin GND; Hoffmann, Donata GND; Mettenleiter, Thomas C. GND; Beer, Martin GND

We inoculated 6 cattle with severe acute respiratory syndrome coronavirus 2 and kept them together with 3 in-contact, virus-naive cattle. We observed viral replication and specific seroreactivity in 2 inoculated animals, despite high levels of preexisting antibody titers against a bovine betacoronavirus. The in-contact animals did not become infected.

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Ulrich, Lorenz / Wernike, Kerstin / Hoffmann, Donata / et al: Experimental infection of cattle with SARS-CoV-2. 2020.

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