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Characterization of mcr-5-Harboring Salmonella enterica subsp. Enterica Serovar Typhimurium Isolates from Animal and Food Origin in Germany

Zugehörigkeit
Department Biological Safety, German Federal Institute for Risk Assessment (BfR), Berlin, Germany
Borowiak, Maria;
Zugehörigkeit
Department Biological Safety, German Federal Institute for Risk Assessment (BfR), Berlin, Germany
Hammerl, Jens A.;
Zugehörigkeit
Department Biological Safety, German Federal Institute for Risk Assessment (BfR), Berlin, Germany
Deneke, Carlus;
Zugehörigkeit
Department Biological Safety, German Federal Institute for Risk Assessment (BfR), Berlin, Germany
Fischer, Jennie;
Zugehörigkeit
Department Biological Safety, German Federal Institute for Risk Assessment (BfR), Berlin, Germany
Szabo, Istvan;
Zugehörigkeit
Department Biological Safety, German Federal Institute for Risk Assessment (BfR), Berlin, Germany
Malorny, Burkhard

We characterized eight mcr-5-positive Salmonella enterica subsp. enterica serovar Typhimurium sequence type 34 (ST34) isolates obtained from pigs and meat in Germany. Five plasmid types were identified harboring mcr-5 on Tn6452 or putative mobile insertion cassettes. The mobility of mcr-5 was confirmed by integration of Tn6452 into the bacterial chromosomes of two strains and the detection of conjugative mcr-5 plasmids. The association with mobile genetic elements might further enhance mcr-5 distribution.

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