Safety and efficacy of L-lysine monohydrochloride and concentrated liquid L-lysine (base) produced by fermentation using Corynebacterium glutamicum strain KCCM 10227 for all animal species

EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)

Following a request from the European Commission, the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on L-lysine monohydrochloride and concentrated liquid L-lysine (base) produced using Corynebacterium glutamicum KCCM 10227 when used as nutritional additives in feed and water for drinking for all animal species. The active substance is L-lysine. L-lysine HCl and concentrated liquid L-lysine (base) produced by the strain C. glutamicum KCCM 10227 do not represent a risk for the target species, the consumer and the environment. L-lysine HCl produced by C. glutamicum KCCM 10227 is hazardous by inhalation, it is not irritant to skin but mildly irritant to eyes and it is not a skin sensitiser. Concentrated liquid L-lysine (base) produced by C. glutamicum KCCM 10227 is hazardous by inhalation, not irritant to skin and eyes and it is not a skin sensitiser. L-lysine HCl and concentrated liquid L-lysine (base) are considered as efficacious sources of the essential amino acid L-lysine for non-ruminant animal species. For the supplemental L-lysine to be as efficacious in ruminants as in non-ruminant species, it would require protection against degradation in the rumen.

Files

Cite

Citation style:

(FEEDAP), EFSA: Safety and efficacy of L-lysine monohydrochloride and concentrated liquid L-lysine (base) produced by fermentation using Corynebacterium glutamicum strain KCCM 10227 for all animal species. 2019.

Rights

Use and reproduction:

Export