Brodifacoum as a first choice rodenticide for controlling bromadiolone-resistant Mus musculus

Laboratory tests were conducted to estimate the efficacy of brodifacoum in controlling bromadioloneresistant Tyr139Cys and Leu128Ser/Tyr139Cys house mice in no-choice feeding tests with two short exposure times of 24 and 48 h. The mortality of bromadiolone-resistant house mice in brodifacoum tests was similar 90 and 100% in the respective 24 and 48 h intervals. There were neither differences in survival rates between the genders nor between the VKOR variants, but consumption was higher in females than in males. Brodifacoum was effective against bromadioloneresistant house mice in the short exposure test, offering a sound practical alternative for rodent control in situations when bromadiolone is no longer a satisfactory solution. Whether a short-term use of brodifacoum after bromadiolone application reduces environmental risks, compared to using brodifacoum only, needs a further confirmation.