Opinion of the Scientific Panel on Additives and Products or Substances used in Animal Feed on the safety of the enzymatic product Avizyme® 1500 for use as feed additive for ducks for fattening

Avizyme 1500 is a multi-enzyme preparation containing xylanase derived from genetically modified Trichoderma longibrachiatum, subtilisin (protease) derived from genetically modified Bacillus subtilis, alpha-amylase produced by Bacillus amyloliquefaciens and polygalacturonase produced by Aspergillus aculeatus. Avizyme 1500 consists of approximately 10% enzyme preparation stabilized onto approximately 90% wheat carrier. It is intended for inclusion in feed rich in starch and non-starch polysaccharides (mainly arabinoxylans and beta-glucans). It has been provisionally authorised for chickens for fattening. The applicant is now seeking an authorisation for Avizyme 1500 for inclusion in feed for ducks to be used throughout the life of the animal. A tolerance test carried out with ducklings over a six week period with the recommended dose (1 g kg-1) and 15-fold overdose (15 g kg-1) of Avizyme 1500 produced no evidence of any adverse effect on performance or mortality. Therefore FEEDAP Panel concluded that the safety of Avizyme 1500 for ducks for fattening has been demonstrated.