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Compatibility of the microbial product 035 ( Bacillus subtilis) with lasalocid sodium, maduramicin ammonium, monensin sodium, narasin, salinomycin sodium and semduramicin sodium

Following a request from the European Commission, the European Food Safety Authority (EFSA) was asked to deliver a scientific opinion on the compatibility of the microbial product 035 (Bacillus subtilis) with lasalocid sodium, maduramicin ammomium, monensin sodium, narasin, salinomycin sodium and semduramicin sodium. Compatibility with lasalocid sodium has been previously established. The applicant provided a 35-day study carried out with 600 chickens, all of which received 035 at the recommended inclusion rate in the presence or absence of the following coccidiostats: salinomycin (70 mg kg-1), narasin (70 mg kg-1), monensin (125 mg kg-1) and maduramycin (5 mg kg-1). At the end of the experiment, caecal samples were randomly collected and analysed for Bacillus. No significant differences in caecal total Bacillus counts were observed between control and coccidiostat-supplemented groups. However, since no treatment was applied to distinguish between spores and vegetative cells, the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) is unable to conclude on the compatibility between 035 and maduramicin ammomium, monensin sodium, narasin and salinomycin sodium. Moreover, in the absence of experimental data, no statement can be made regarding semduramicin sodium.

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