Scientific Opinion on the safety and efficacy of AveMix® XG 10 (endo-1,4- beta-xylanase and endo-1,3(4)-beta-glucanase) as feed additive for weaned piglets

The additive AveMix® XG 10 is an enzyme preparation of endo-1,4-beta-xylanase and endo-1,3(4)-betaglucanase, produced by two strains of Trichoderma reesei. This product is currently authorised for use in chickens for fattening as a zootechnical additive, under the functional group of digestibility enhancers. The applicant is now seeking for an extension of the authorisation to weaned piglets at a recommended dose of 4000 XU and 900 BGU/kg complete feed. Since piglets tolerated a 100-fold overdose, the FEEDAP Panel concludes that AveMix® XG 10 is safe for weaned piglets at the recommended dose. Supplementation of the diets with the additive at the recommended dose resulted in a significantly higher body weight gain of piglets in one trial and better feed to gain ratio in two trials. Therefore, the FEEDAP Panel concludes that AveMix® XG 10 has the potential to be efficacious at this dose.