An R-like protein of Streptococcus uberis stimulates opsonising antibodies

A pepsin-sensitive R-like antigen with a molecular mass of 65 kilodaltons was extracted from Streptococcus uberis strain ATCC 19436 by trypsinisation and purified by diethyl-aminoethanol anionic exchange chromatography. The antigen reacted with sera from infected cows and stimulated opsonic antibody in the guinea pig. The amino acid composition of the antigen was generally similar to that previously reported for the R antigen of group C streptococci.