Reverse Genetics Systems for Filoviruses

Hoenen, Thomas GND; Feldmann, H.

Filoviruses are among the most pathogenic viruses known to man. Reverse genetics systems, in particular full-length clone systems, allow the generation of recombinant filoviruses, which can be used to study virus biology, but also for applied uses such as screening for countermeasures. Here we describe the generation of recombinant filoviruses from cDNA.

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Hoenen, Thomas / Feldmann, H.: Reverse Genetics Systems for Filoviruses. 2017.

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