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Failure to induce formation of proteinase K resistant fibrils in pigeons through experimental infection with paramyxovirus type 1

Ten racing pigeons were infected experimentally with the paramyxovirus (PMV) type 1 of the pigeon. Within twelve weeks of observation, they were euthanized at different times. Their brains were examined for proteinase K resistant fibrils and histopathologically for spongiform lesions. No proteinase K resistant fibrils and no spongiform lesions could be detected in any case. Therefore, it is estimated that PMV type 1 of the pigeon is not likely to induce pathogenic mechanisms assumed for transmissible spongiform encephalopathies.

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