Molecular fingerprinting of Mycobacterium bovis subsp. caprae isolates from Central Europe

Erler, W.; Martin, Gerald GND; Sachse, Konrad GND; Naumann, L.; Kahlau, D.; Beer, J.; Bartos, M.; Nagy, G.; Cvetnic, Z.; Zolnir-Dovc, M.; Pavlik, I.

To study the dissemination of Mycobacterium bovis subsp. caprae, 79 European isolates from cattle, humans, and other hosts were examined by spoligotyping and IS6110 restriction fragment length polymorphism (RFLP) analysis. Among a total of 11 different spoligotypes identified, type C1 proved to be predominant (n62). Five of the spoligotypes are described for the first time. A total of 43 different RFLP types were identified, thus allowing further differentiation for epidemiological tracking. Isolates from a series of outbreaks in one village proved to be of the same spoligotype and of identical or closely related RFLP types.

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Erler, W. / Martin, Gerald / Sachse, Konrad / et al: Molecular fingerprinting of Mycobacterium bovis subsp. caprae isolates from Central Europe. 2004.

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