Rapid and highly sensitive pathotyping of avian influenza A H5N1 virus by using real-time reverse transcription-PCR

Hoffmann, Bernd; Harder, Timm C.; Starick, Elke; Depner, Klaus Robert; Werner, Ortrud; Beer, Martin

doi:10.1128/JCM.01681-06

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Rapid and highly sensitive pathotyping of avian influenza A H5N1 virus by using real-time reverse transcription-PCR

Hoffmann, Bernd ; Harder, Timm C.; Starick, Elke ; Depner, Klaus Robert ; Werner, Ortrud ; Beer, Martin

Rapid typing of the pathogenicity of avian influenza A viruses (AIV) of subtypes H5 and H7 is crucial to initiate adequate protective measures preventing the spread of highly pathogenic AIV (HPAIV). Here, a new real-time reverse transcription-PCR assay which enables sensitive and specific detection and cleavage site analysis of HPAIV H5N1 of the Qinghai lineage is described

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Erschienen in:: Journal of clinical microbiology
Vol. 45, H. 2 (2007), S. 600-603
Band:: 45
Heft:: 2
Datum der Veröffentlichung:: 20.12.2006
DOI:: 10.1128/JCM.01681-06
Sprache:: Englisch
Ressourcentyp:: Text
Schlagwörter:: hemagglutinin cleavage; subtypes
DDC-Sachgruppe der DNB:: 630 Landwirtschaft, Veterinärmedizin
Link URL:: http://jcm.asm.org/content/45/2/600
Link URL:: http://www.ncbi.nlm.nih.gov/pmc/articles/pmid/17182758/
Einrichtung:: Friedrich-Loeffler-Institut, Institut für Virusdiagnostik
Physischer Standort:: SD/2007/128