Novel varicella-zoster virus glycoprotein E gene mutations associated with genotypes A and D

Schmidt-Chanasit, J.; Bleymehl, K.; Schad, S.G.; Gross, G.; Ulrich, Rainer G.; Doerr, H.W.

doi:10.1128/JCM.01735-07

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Novel varicella-zoster virus glycoprotein E gene mutations associated with genotypes A and D

Schmidt-Chanasit, J.; Bleymehl, K.; Schad, S.G.; Gross, G.; Ulrich, Rainer G.; Doerr, H.W.

Here, we describe the association of certain varicella-zoster virus (VZV) genotypes with unique glycoprotein E (gE) gene mutations. Within 45 analyzed VZV wild-type strains of genotypes A and D, five novel gE mutations were discovered. A statistically significant (P < 0.0001) association of certain gE mutations with VZV genotype D was found

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Erschienen in:: Journal of clinical microbiology
Vol. 46, H. 1 (2008), S. 325-327
Band:: 46
Heft:: 1
Datum der Veröffentlichung:: 21.11.2007
DOI:: 10.1128/JCM.01735-07
Sprache:: Englisch
Ressourcentyp:: Text
Schlagwörter:: ASSOCIATION; E EPITOPE; GENE; GENOME; GERMANY; GLYCOPROTEIN; SEQUENCE; SINGLE NUCLEOTIDE POLYMORPHISMS; STRAINS; VIRUS
DDC-Sachgruppe der DNB:: 570 Biowissenschaften, Biologie
Link URL:: http://jcm.asm.org/content/46/1/325.long
Link URL:: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2224269/
Einrichtung:: Friedrich-Loeffler-Institut, Institut für neue und neuartige Tierseuchenerreger
Physischer Standort:: SD/2008/40