Highly pathogenic avian influenza virus (H5N1) in experimentally infected adult mute swans: Pathogenicity of Highly Pathogenic Avian Influenza Virus (H5N1) in Adult Mute Swans

Hoffmann, Donata; Breithaupt, Angele; Teifke, Jens Peter; Globig, Anja; Harder, Timm C.; Mettenleiter, Thomas C.; Beer, Martin

doi:10.3201/eid1408.080078

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Highly pathogenic avian influenza virus (H5N1) in experimentally infected adult mute swans : Pathogenicity of Highly Pathogenic Avian Influenza Virus (H5N1) in Adult Mute Swans

Hoffmann, Donata ; Breithaupt, Angele ; Teifke, Jens Peter ; Globig, Anja ; Harder, Timm C.; Mettenleiter, Thomas C.; Beer, Martin

Adult, healthy mute swans were experimentally infected with highly pathogenic avian influenza virus A/Cygnus cygnus/Germany/R65/2006 subtype H5N1. Immunologically naive birds died, whereas animals with preexisting, naturally acquired avian influenza virus-specific antibodies became infected asymptomatically and shed virus. Adult mute swans are highly susceptible, excrete virus, and can be clinically protected by preexposure immunity

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Erschienen in:: Emerging infectious diseases
Vol. 14, H. 8 (2008), S. 1267-1270
Band:: 14
Heft:: 8
Datum der Veröffentlichung:: 01.08.2008
DOI:: 10.3201/eid1408.080078
Sprache:: Englisch
Ressourcentyp:: Text
Schlagwörter:: antibody; avian influenza; BIRDS; GERMANY; H5N1; highly pathogenic; highly pathogenic avian influenza; IMMUNITY; PATHOBIOLOGY; SUBTYPE H5N1; VIRUS
DDC-Sachgruppe der DNB:: 630 Landwirtschaft, Veterinärmedizin
Link URL:: http://wwwnc.cdc.gov/eid/article/14/8/08-0078_article.htm
Link URL:: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2600380/
Einrichtung:: Friedrich-Loeffler-Institut, Institut für Virusdiagnostik
Einrichtung:: Friedrich-Loeffler-Institut, Institut für Infektionsmedizin
Einrichtung:: Friedrich-Loeffler-Institut, Leitungsbereich
Einrichtung:: Friedrich-Loeffler-Institut, Institut für molekulare Virologie und Zellbiologie
Physischer Standort:: SD/2008/43