Highly pathogenic avian influenza virus (H5N1) in experimentally infected adult mute swans : Pathogenicity of Highly Pathogenic Avian Influenza Virus (H5N1) in Adult Mute Swans

Hoffmann, Donata GND; Breithaupt, Angele GND; Teifke, Jens Peter GND; Globig, Anja GND; Harder, Timm C. GND; Mettenleiter, Thomas C. GND; Beer, Martin GND

Adult, healthy mute swans were experimentally infected with highly pathogenic avian influenza virus A/Cygnus cygnus/Germany/R65/2006 subtype H5N1. Immunologically naive birds died, whereas animals with preexisting, naturally acquired avian influenza virus-specific antibodies became infected asymptomatically and shed virus. Adult mute swans are highly susceptible, excrete virus, and can be clinically protected by preexposure immunity

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Hoffmann, Donata / Breithaupt, Angele / Teifke, Jens Peter / et al: Highly pathogenic avian influenza virus (H5N1) in experimentally infected adult mute swans. Pathogenicity of Highly Pathogenic Avian Influenza Virus (H5N1) in Adult Mute Swans. 2008.

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