Molecular Basis of Sulfonamide and Trimethoprim Resistance in Fish-Pathogenic Aeromonas Isolates

Kadlec, Kristina; Czapiewski, Ellen von; Kaspar, H.; Wallmann, J.; Michael, Geovana Brenner; Steinacker, U.; Schwarz, Stefan

doi:10.1128/AEM.00560-11

refereed

published

Molecular Basis of Sulfonamide and Trimethoprim Resistance in Fish-Pathogenic Aeromonas Isolates

Kadlec, Kristina ; Czapiewski, Ellen von ; Kaspar, H.; Wallmann, J.; Michael, Geovana Brenner ; Steinacker, U.; Schwarz, Stefan

Sulfonamide-trimethoprim-resistant Aeromonas salmonicida and motile Aeromonas spp. from diseased fish of the GERM-Vet study carried the sul1 gene together with mostly cassette-borne trimethoprim resistance genes, including the novel gene dfrA28. The seven dfrA and dfrB genes identified were mostly located in class 1 integrons which commonly harboured other gene cassettes