5th World Congress on Alternatives & Animal Use in the Life Sciences

Inhalt

• The use of serum-free culture conditions in the embryonic stem cell test: defined culture conditions for cardiac stem cell differentiation.

  Schlechter,K.; Buesen,R.; Slawik,B.; Spielmann,H.; Seiler,A.

• The use of toxicogenomics in risk assessment: perspectives and challenges

  Gundert-Remy,U.; Richter-Reichhelm,H.B.; Oberemm,A.

• The combined use of (Q)SARs and in vitro testing methods for creating intelligent testing strategies for local effects - potential and current limitations.

  Herzler,M.; Liebsch,M.; Spielmann,H.; Gerner,I.

• Proposal for modification of the Embryonic Stem Cell Test to expand its applicability.

  Koichi,I.; Spielmann,H.; Nakamura,M.

• Prevalidation study on testing percutaneous absorption via reconstructed human epidermis.

  Bock,U.; Haltner,E.; Kaca,M.; Kietzmann,M.; Korting,H.C.; Lehr,C.M.; Liebsch,M.; Netzlaff,F.; Niedorf,F.; Rübbelke,M.K.; Schäfer,U.F.; Schmidt,E.; Schreiber,S.; Grabiel Vuia,A.; Schäfer-Korting,M.

• On the replacement of in vivo tests on germ cell mutagenicity and fertility impairment

  Vogel,R.; Klemm,M.; Genschow,E.; Seiler,A.; Liebsch,M.; Spielmann,H.

• In vitro embryotoxicity testing of some components of dental biomaterials by the Embryonic Stem Cell Test.

  Koichi,I.; Spielmann,H.; Hayakawa,T.; Nakamura,M.

• Expansion of the Embryonic Stem Cell Test: Differentiation into neural cells

  Hayess,K.; Buesen,R.; Schlechter,K.; Slawik,B.; Spielmann,H.; Seiler,A.

• Establishing predictive molecular markers of differentiation as toxicological endpoints in the Embryonic Stem Cell test (EST)

  Buesen,R.; Kaltenhäuser,J.; Genschow,E.; Visan,A.; Slawik,B.; Schlechter,K.; Becker,K.; Spielmann,H.; Seiler,A.

• Assessment of the performance of in vitro photogenotoxicity assays: Results of a collaborative study with 13 coded test chemicals

  Kasper,P.; Aeby,P.; Brendler-Schwaab,S.; Epe,B.; Frötschl,R.; Hertel,C.; Kirchner,S.; Liebsch,M.; Meurer,K.; Plappert-Helbig,U.; Schmidt,E.

• Assessment of the Halle Register for classifying and labelling new chemicals according to the EU toxicity classes.

  Genschow,E.; Traue,D.; Halle,W.; Liebsch,M.; Spielmann,H.

• A prevalidation of in-vitro photo genotoxicity tests and the effort to find a useful statistical prediction model.

  Schmidt,E.; Aeby,P.; Brendler-Schwaab,S.; Epe,B.; Frötschl,R.; Gocke,E.; Hertel,C.; Kasper,P.; Kirchner,S.; Liebsch,M.; Meurer,K.; Plappert-Helbig,U.