- Beitrag
- Advancing the science of developmental neurotoxicity (DNT): Testing for…
Advancing the science of developmental neurotoxicity (DNT): Testing for better safety evaluation
Vorschau
Einordnung
- Erschienen in:
-
ALTEX - Alternatives to animal experimentation
Vol. 29, H. 2 (2012), S. 202-215 - Band:
- 29
- Heft:
- 2
- Datum der Veröffentlichung:
- 2012
- Sprache:
- Englisch
- Ressourcentyp
: - Text
- Schlagwörter:
- 3; ACTIVATION; acute; adverse effects; Algorithms; alternative; alternative method; alternative methods; analysis; animal testing alternative; Animal Testing Alternatives; Animals; Apoptosis; approach; ARRAYS; article; ASSAY; assessment; ASSOCIATION; biology; Biomarker; biomarkers; BIPHENYLS; blood; BRAIN; calcium; CALIFORNIA; cancer; CELL; cell culture; Cell Differentiation; Cell Line; CELL-CULTURES; CELL-LINE; CELLS; Cells,Cultured; Central Nervous System; CENTRAL-NERVOUS-SYSTEM; changes; chemical; chemical substance; CHEMICAL-SUBSTANCES; chemicals; Child; CHILDREN; comparative; comparison; conference; conference paper; congresses; Congresses as Topic; consumer; Consumer Protection; control; CULTURE; CULTURES; CYP1A1; Danio; Danio rerio; DANIO-RERIO; DETECT; development; developmental disorder; developmental neurotoxicity; diagnostic; DIFFERENTIATION; DISEASE; DRUG; drugs; effect; EFFECTS; Embryo; embryonic stem cell; embryonic stem cell test; embryonic stem cells; embryotoxicity; EMBRYOTOXICITY TEST; endocrine; Endocrine Disruption; ENDPOINTS; Environmental; environmental chemical; environmental chemicals; environmental protection; epidemiology; Epigenomics; ESTABLISHMENT; evaluation; exposure; EXPRESSION; Fibroblasts; FORM; Framework; France; gene; gene expression; Gene Expression Regulation,Developmental; GENE-EXPRESSION; GENES; genomic; german; growth; growth factor; GROWTH-FACTOR; guideline; Guidelines; hazard; Hazardous Substances; HEALTH; health effects; health risk; HEALTH RISK ASSESSMENT; health risks; high throughput screening; hormone; Human; Humans; IMPACT; In Vitro; in vitro test; In vitro tests; in vivo; IN-UTERO; IN-VITRO; IN-VIVO; INDUCE; industrial chemicals; Industry; INHIBITION; INSIGHTS; international; investigation; ISSUES; Italy; lead; Legislation,Drug; line; liver; LONG-TERM; Male; MAMMALS; MECHANISM; MECHANISMS; method; methods; migration; model; Models; Molecular mechanisms; MOUSE; Nervous System; neurite outgrowth; neurologic examination; neurology; neurons; neurotoxicity; Neurotoxicity Syndromes; nonhuman; note; NUMBER; Occupational Exposure; OCCUPATIONAL-EXPOSURE; OECD; ORIGIN; ORIGINS; PAH; PAHs; Parkinson's disease; PATHWAY; PATHWAYS; PCB; PERFORMANCE; pesticide; Pesticides; Phenotype; physiological; poisoning; pollution; polybrominated diphenyl ether; polychlorinated biphenyls; POLYCHLORINATED-BIPHENYLS; potential; PREDICT; Pregnancy; Prevalence; prevention; project; proliferation; PROTECTION; protein; Proteins; QUANTITATION; Rat; RECOMMENDATIONS; reference; regulation; reliability; Report; reproducibility; REPRODUCTIVE TOXICITY; Research; response; RESPONSES; review; Risk; Risk Assessment; RISK-ASSESSMENT; Safety; SAFETY EVALUATION; SCIENCE; screening; searching; SENSITIVITY; SERA; serine; serum; SIGNAL; Signal Transduction; Species Specificity; SPECTRA; SPECTRUM; STATE; Stem Cells; STRATEGIES; strategy; studies; study; SUBSTANCES; SYSTEM; SYSTEMS; TARGET; TARGETS; TCDD; TECHNOLOGIES; TECHNOLOGY; test guideline; Testing; TESTS; thyroid hormone receptors; THYROID-HORMONE; tissue; tissues; toxic; toxicity; toxicity testing; Toxicity Tests; toxicology; transgenic; trends; United States; UNITED-STATES; validation; VITRO; VIVO; Zebrafish
- Link URL:
- http://www.altex.ch/All-issues/Issue.50.html?iid=131&aid=7
- Einrichtung:
- Bundesinstitut für Risikobewertung, Bundesinstitut für Risikobewertung (bis Juni 2014), Abteilung 9 - Experimentelle Toxikologie und ZEBET (bis Juni 2014), Fachgruppe 92 - ZEBET - Alternativmethoden zu Tierversuchen
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