Detection of hepatitis E virus in archived German wild boar serum samples

Kaci, S.; Nöckler, K.; Johne, R.

doi:10.1016/j.vetmic.2007.10.030

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Detection of hepatitis E virus in archived German wild boar serum samples

Hepatitis E is a rare human disease in Central Europe commonly imported from endemic regions. For autochthonous infections a zoonotic transmission from pigs, deer and wild boar is assumed. Using three different RT-PCR protocols, hepatitis E virus (HEV) RNA was detected in 10 out of 189 (5.3%) serum samples collected in 1995/1996 from wild boars in Germany. Sequence analysis indicates a close relationship with genotype 3 isolates of pigs and humans from the Netherlands and Japan. The results indicate that HEV is present in Germany since more than 10 years and that wild boar may function as a reservoir for HEV

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Erschienen in:: Veterinary microbiology
Vol. 128, H. 3-4 (2008), S. 380-385
Band:: 128
Heft:: 3-4
Datum der Veröffentlichung:: 2008
DOI:: 10.1016/j.vetmic.2007.10.030
Sprache:: Englisch
Ressourcentyp:: Text
Schlagwörter:: analysis; Animals; Animals,Wild; article; assessment; Berlin; Capsid Proteins; classification; DEER; detection; DISEASE; Disease Reservoirs; epidemiology; Europe; Female; Gene Amplification; genetics; Genotype; Germany; Hepatitis E; Hepatitis E virus; Human; Humans; INFECTION; INFECTIONS; isolation & purification; Japan; Male; Phylogeny; pig; PIGS; Prevalence; protein; Proteins; PROTOCOL; REGION; Research; Reverse Transcriptase Polymerase Chain Reaction; Risk; Risk Assessment; RISK-ASSESSMENT; Rna,Viral; RT-PCR; SAMPLES; SEQUENCE; SEQUENCE-ANALYSIS; SERA; serum; Species Specificity; Sus scrofa; Swine Diseases; transmission; veterinary; virology; wild boar; WILD BOARS; Zoonoses
DDC-Sachgruppe der DNB:: 600 Technik
Link URL:: http://www.sciencedirect.com/science/article/pii/S0378113507005342
Einrichtung:: Bundesinstitut für Risikobewertung, Bundesinstitut für Risikobewertung (bis Juni 2014), Abteilung 4 - Biologische Sicherheit (bis Juni 2014), Fachgruppe 42 - Lebensmittelhygiene und Sicherheitskonzepte
Einrichtung:: Bundesinstitut für Risikobewertung, Bundesinstitut für Risikobewertung (bis Juni 2014), Abteilung 4 - Biologische Sicherheit (bis Juni 2014), Fachgruppe 45 - Diagnostik, Genetik und Erregercharakterisierung