The practical application of three validated in vitro embryotoxicity tests - The Report and Recommendations of an ECVAM/ZEBET Workshop (ECVAM Workshop 57)

Spielmann, H.; Seiler, A.; Bremer, S.; Hareng, L.; Hartung, T.; Ahr, H.; Faustman, E.; Haas, U.; Moffat, G. J.; Nau, H.; Vanparys, P.; Piersma, A.; Sintes, J. R.; Stuart, J.

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The practical application of three validated in vitro embryotoxicity tests - The Report and Recommendations of an ECVAM/ZEBET Workshop (ECVAM Workshop 57)

Spielmann, H.; Seiler, A.; Bremer, S.; Hareng, L.; Hartung, T.; Ahr, H.; Faustman, E.; Haas, U.; Moffat, G. J.; Nau, H.; Vanparys, P.; Piersma, A.; Sintes, J. R.; Stuart, J.

The major limitations of the validated in vitro embryotoxicity tests identified at the 2003 workshop were immediately taken into account by ECVAM in a proposal for an Integrated Project in the EU 6th Framework Programme, entitled ReProTect (22). Since 2004, a consortium of more than 36 laboratories involved in this project have been evaluating existing and newly developed in vitro models for reproductive processes and their integration into a testing strategy. This strategy should provide detailed information on the hazard potentials of chemicals to the mammalian reproductive cycle

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Erschienen in:: Alternatives to laboratory animals : ATLA
Vol. 34, H. 5 (2006), S. 527-538
Band:: 34
Heft:: 5
Datum der Veröffentlichung:: 2006
Sprache:: Englisch
Ressourcentyp:: Text
Schlagwörter:: article; ASSAY; assessment; Berlin; chemical; chemicals; COMMUNITY; consumer; Denmark; ECVAM; effect; EFFECTS; embryotoxicity; EMBRYOTOXICITY TEST; END-POINTS; EU; EXPRESSION; Food; food safety; Germany; hazard; In Vitro; IN-VITRO; INFORMATION; INTEGRATION; Laboratories; method; methods; model; Models; potential; PREDICTION MODELS; project; RECOMMENDATIONS; reference; REPRODUCTIVE TOXICITY; Risk; Risk Assessment; RISK-ASSESSMENT; Safety; STEM-CELL TEST; STRATEGIES; strategy; Testing; TESTING STRATEGIES; testing strategy; TESTS; TIME; TIMES; VITRO; VITRO EMBRYOTOXICITY TESTS; workshop
DDC-Sachgruppe der DNB:: 600 Technik
Link URL:: http://ecvam.jrc.it/publication/WorkshopReport57.pdf
Einrichtung:: Bundesinstitut für Risikobewertung, Bundesinstitut für Risikobewertung (bis Juni 2014), Abteilung 3 - Wissenschaftliche Querschnittsaufgaben (bis Juni 2014)