Determination of polar pharmaceuticals in sewage water of Greece by gas chromatography-mass spectrometry

Koutsouba, V.; Heberer, T.; Fuhrmann, B.; Schmidt-Baumler, K.; Tsipi, D.; Hiskia, A.

doi:10.1016/S0045-6535(02)00819-6

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Determination of polar pharmaceuticals in sewage water of Greece by gas chromatography-mass spectrometry

Koutsouba, V.; Heberer, T.; Fuhrmann, B.; Schmidt-Baumler, K.; Tsipi, D.; Hiskia, A.

Sewage influents and effluents of different urban areas of Greece, were analyzed for polar pharmaceutical residues, used in human medicine. Drugs investigated were the anti-inflammatory drugs diclofenac and ibuprofen, the metabolite of the drugs clofibrates used as blood lipid regulators, clofibric acid and the analgesics phenazone and propyphenazone. Analysis was carried out using capillary gas chromatography-mass spectrometry with selected ion monitoring. The method used was involved solid phase extraction (C-18) and derivatization with pentafluorobenzyl bromide. Diclofenac was detected in every sewage effluent sample. (C) 2003 Elsevier Science Ltd. All rights reserved

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Erschienen in:: Chemosphere
Vol. 51, H. 2 (2003), S. 69-75
Band:: 51
Heft:: 2
Datum der Veröffentlichung:: 2003
DOI:: 10.1016/S0045-6535(02)00819-6
Sprache:: Englisch
Ressourcentyp:: Text
Schlagwörter:: ACID; ACIDIC HERBICIDES; analysis; article; Berlin; blood; CHROMATOGRAPHY-MASS SPECTROMETRY; CLOFIBRIC ACID; CONTAMINANTS; DERIVATIZATION; Determination; diclofenac; DRINKING-WATER; DRUG; DRUG RESIDUES; drugs; EFFLUENTS; ENVIRONMENT; EXTRACTION; Food; Gas Chromatography-Mass Spectrometry; Germany; Human; ibuprofen; metabolite; method; monitoring; new environmental contaminants; Pesticide Residues; PESTICIDE-RESIDUES; PHARMACEUTICAL RESIDUES; pharmaceuticals; PHASE; propyphenazone; reference; residue; RESIDUES; SAMPLES; SCIENCE; SEWAGE; SPECTROMETRY; SURFACE WATERS; TIME; TIMES; TREATMENT PLANTS; WASTE-WATER; WATER
DDC-Sachgruppe der DNB:: 600 Technik
Link URL:: http://www.sciencedirect.com/science/article/pii/S0045653502008196
Einrichtung:: Bundesinstitut für Risikobewertung, Bundesinstitut für Risikobewertung (bis Juni 2014), Abteilung 6 - Chemikaliensicherheit (bis Juni 2014)