Determination of Veterinary Drug Residues Using Liquid Chromatography and Tandem Mass Spectrometry

Balizs, G.; Hewitt, A.

This paper describes the principles, the current technology and the applications of HPLC and tandem mass spectrometry (LC-MS-MS) in the analysis of veterinary drug residues. Since the development of commercial atmospheric pressure interfaces, capable of coupling HPLC to mass spectrometer, LC-MS-MS has become widely used as a complementary technique to GC-MS in residue analysis because of its applicability to the determination of polar and/or non-volatile compounds without derivatization. This technique includes electrospray and atmospheric pressure chemical ionization.

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Balizs, G. / Hewitt, A.: Determination of Veterinary Drug Residues Using Liquid Chromatography and Tandem Mass Spectrometry. 2003.

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