Determination of Veterinary Drug Residues Using Liquid Chromatography and Tandem Mass Spectrometry

Balizs, G.; Hewitt, A.

doi:10.1016/S0003-2670(03)00890-0

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Veröffentlicht

Determination of Veterinary Drug Residues Using Liquid Chromatography and Tandem Mass Spectrometry

This paper describes the principles, the current technology and the applications of HPLC and tandem mass spectrometry (LC-MS-MS) in the analysis of veterinary drug residues. Since the development of commercial atmospheric pressure interfaces, capable of coupling HPLC to mass spectrometer, LC-MS-MS has become widely used as a complementary technique to GC-MS in residue analysis because of its applicability to the determination of polar and/or non-volatile compounds without derivatization. This technique includes electrospray and atmospheric pressure chemical ionization.

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Einordnung

Erschienen in:: Analytica chimica acta : an international journal devoted to all branches of analytical chemistry
Vol. 492, H. 1-2 (2003), S. 105-131
Band:: 492
Heft:: 1-2
Datum der Veröffentlichung:: 2003
DOI:: 10.1016/S0003-2670(03)00890-0
Sprache:: Englisch
Ressourcentyp:: Text
Schlagwörter:: analysis; chemical; CHROMATOGRAPHY; compounds; DERIVATIZATION; Determination; development; DRUG; DRUG RESIDUES; HPLC; Liquid Chromatography; LIQUID-CHROMATOGRAPHY; Mass Spectrometry; MASS-SPECTROMETRY; Pressure; residue; RESIDUES; SPECTROMETRY; Tandem Mass Spectrometry; technique; TECHNOLOGIES; TECHNOLOGY; veterinary; veterinary drug
DDC-Sachgruppe der DNB:: 600 Technik
Link URL:: http://www.sciencedirect.com/science/article/pii/S0003267003008900
Einrichtung:: Bundesinstitut für Risikobewertung, Bundesinstitut für Risikobewertung (bis Juni 2014), Abteilung 5 - Lebensmittelsicherheit (bis Juni 2014)